GLUTARALDEHYDE
SYNONYMS:
CIDEX;
CUDEX; 1,3-DIFORMAL PROPANE; EEC No. 605-022-00-X; GLUTAMIC DIALDEHYDE;
GLUTARAL; GLUTARD DIALDEHYDE; GLUTARIC ACID DIALDEHYSE; GLUTARIC DIALDEHYDE;
NCI-C55425; PENTANEDIAL; 1,5-PENTANEDIAL; 1,5-PENTANEDIONE; POTENTIATED ACID
GLUTARALDEHYDE; SONACIDE; UCONEX
®
IDENTIFICATION:
CAS:
111-30-8
DOT ID:
UN2810
Hazard class or Division:
6.1 (POISONOUS/TOXIC MATERIALS)
ERG Guide:
Formula:
C5H8O2;
HCO(CH2)3CHO
RTECS No:
MA2450000
Properties:
Colorless
liquid with a pungent odor, which readily changes to a glossy polymer. Soluble
in water.
Uses:
In
controlling bacteria and fungi in aqueous metalworking fluids.
HEALTH & SAFETY INFORMATION
•
Testing by NIOSH has not been completed to determine the carcinogenicity of
glutaraldehyde and related low molecular weight aldehydes. However, the limited
studies to date indicate that these substances have chemical reactivity and
mutagenicity similar to acetaldehyde and malonaldehyde. Therefore, NIOSH
recommends that careful consideration should be given to reducing exposures to
related aldehydes such as gluteraldehyde.
Animal studies
: Exposure to acetaldehyde has produced nasal tumors in rats and
laryngeal tumors in hamsters, and exposure to malonaldehyde has produced
thyroid gland and pancreatic islet cell tumors in rats. Further information can
be found in NIOSH Publication No. 91-112.
•
OSHA Table Z-1-A Air Contaminant
•
Irritates the eyes, skin, and respiratory tract.
Inhalation:
0.3 ppm can cause nose and throat irritation.
0.4 ppm has caused headaches. 0.5 ppm has been described as intolerably
irritating.
Skin:
Can be absorbed through the skin. Can cause
irritation. Contact with a 5% solution can sensitize the skin andcause an
allergic response to subsequent contact of much lower concentrations.
Eyes:
Vapors of a 2% solution (0.4 ppm) have
produced irritation.
Ingestion:
Causes irritation of the
mouth and stomach. The LD50: (oral rat) = 134 mg/kg (moderately toxic).
Repeated or prolonged contact with skin may cause chemical sensitization,
dermatitis, skin allergy, cough, nausea, vomiting and asthma. Exposure may
cause liver and nervous system damage. Glutaraldehyde may cause mutations,
handle with extreme caution.
Exposure Limits:
•
ACGIH TLV: 0.05 ppm, ceiling limit, sensitizer, not classifiable as a human
carcinogen
•
OSHA PEL: None
•
NIOSH REL: 0.2 ppm/0.8 mg/m3, ceiling limit
•
DFG MAK: 0.1 ppm/0.42 mg/m3
Respirator:
0.2
ppm:
use an MSHA/NIOSH
approved respirator with an organic vapor cartridge/canister and a
dust/mist/fume prefilter. More protection is provided by a full facepiece
respirator than by a half-mask respirator, and even greater protection is
provided by a powered-air purifying respirator. Where the potential for high
exposures exists, use an MSHA/NIOSH approved supplied-air respirator with a
full facepiece operated in the positive pressure mode or with a full facepiece,
hood, or helmet in the continuous flow mode, or use an MSHA/NIOSH approved
selfcontained breathing apparatus with a full facepiece operated in
pressure-demand or other positive pressure mode.
Reactivity:
Water
contact forms a polymer solution. A strong reducing agent. Incompatible with
strong acids, caustics, ammonia, amines, strong oxidizers.
Note:
Alkaline solutions of glutaraldehyde (i.e.,
activated glutaraldehyde) react with alcohol, ketones, amines, hydrazines and
proteins.
FIRE INFORMATION
Firefighting
gear (including SCBA) does not provide adequate protection. If exposure occurs,
remove and isolate gear immediately and thoroughly decontaminate personnel.
Vapors are heavier than air and will collect in low areas. Vapors in confined
areas may explode when exposed to fire. Vapors may travel long distances to
ignition sources and flashback. Storage containers and parts of containers may
rocket great distances, in many directions. If material or contaminated runoff
enters waterways, notify downstream users of potentially contaminated waters.
Notify local health and fire officials and pollution control agencies. Use dry
chemicals, foam, carbon dioxide. From a secure explosion-proof location, use
water spray to cool exposed containers. If cooling streams are ineffective (venting
sound increases in volume and pitch, tank discolors or shows any signs of
deforming), withdraw immediately to a secure position.
Hazard Classifications:
Health Hazard (Blue)
. . . . . . . . . . . . . . 2
Flammability (Red)
. . . . . . . . . . . . . . . 0
Reactivity (Yellow)
. . . . . . . . . . . . . . . . 0
FIRST AID:
If
this chemical gets into the eyes, remove any contact lenses at once and
irrigate immediately for at least 30 minutes, occasionally lifting upper and
lower lids. Seek medical attention immediately. If this chemical contacts the
skin, remove contaminated clothing and wash immediately with soap and water.
Seek medical attention immediately. If this chemical has been inhaled, remove
from exposure, begin rescue breathing (using universal precautions) if
breathing has stopped and CPR if heart action has stopped. Transfer promptly to
a medical facility. When this chemical has been swallowed, get medical
attention. Give large quantities of water and induce vomiting. Do not make an
unconscious person vomit.
ENVIRONMENTAL REGULATIONS
•
California LOL: GMNP
•
WHMIS, Ingredients Disclosure List (Canada): 1%